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High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor

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High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor

China High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor supplier

Large Image :  High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor

Product Details:

Place of Origin: China
Brand Name: Hezhong
Certification: ISO9001
Model Number: 220127-57-1
Packing:: 25kg/drum or as require
Email:: vicky@chembj.com
Skype:: supersteroids
Mobile:: 0086 18872220733

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: negotiable
Packaging Details: 25kg/drum or as required
Delivery Time: 4-6 working days
Payment Terms: Western Union, MoneyGram, T/T, PayPal,Bank Transfer
Supply Ability: 1000kg per Month
Delivery:: By DHL, TNT, FedEx, HKEMS, UPS, etc.
Lead Time:: Within 12 hours upon receipt of payment
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Detailed Product Description
Assay: 99% Molecular Formula: C30H35N7O4S
M.W.: 589.71 Packing: 25kg/drum
Appearance: Off-White Powder

High Purity Anti-cancer Imatinib mesylate/220127-57-1 Tyrosine-kinase Inhibitor

 

 

1. Quick Details:

 

Product Name: Imatinib Mesylate

Synonyms :  GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)

CAS NO.: 220127-57-1

Molecular Formula : C30H35N7O4S

Molecular weight: 589.71

Documents: GMP

Quality: 99%up by HPLC

Usage: Anti tumor drugs

Storage: Preserve in well-closed containers, keep from light and store below 30 °C

 

2. Product Description:

 

Chemical name

Imatinib Mesylate

CAS NO.

220127-57-1

Synonyms

GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)

Melting point

183-185°C

Molecular Formula

C30H35N7O4S

Molecular Weight

589.71

Boiling Point

754.9 °C at 760 mmHg

Flash point

410.3 °C

Appearance

Off-white solid

Application

Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies

 

3. Application:

 

A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)

Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, cKit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib.

 

4. Specification:

 

COA

Item

Acceptance criteria

Result

Appearance

White or almost white powder

white powder

Solubility

Easy to dissolve in the water

Complies

Identification

High-performance liquid chromatograph

HPLC

Almost the same

Infrared absorption

Almost the same

Melting point

222-227°C

223-224º°C

Water

≤0.5%

0.2%

Heavy metals

≤10ppm

Complies

Residue on ignition

≤0.1%

0.03%

Related impurity

Sigle impurity≤0.5%

0.07%

Total impurity no more than 1.0%

0.11%

HPLC assay

98.0%~102.0%

99.9%

 

5. Packaging & Delivery:
 
        We have sufficient stock and can delivery promptly at the very day when receive the payment. The Sophisticated and professional logistic agent will coordinate with us to provide our customers with fast delivery and secure shipping. We also have well- trained and disciplined packing team. It will be arranged in fast and discreet shipment for customs pass Guaranteed. At the same time, packing pictures and tacking code will be provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day. We pay much attention to after- sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.
 
6. Competitive Advantages:
 
1. High quality and good price.
2. Delivey in time.
3. 100% customs pass guaranteed.
4. Good after-sale service. Solve your problems in time.

High Purity Anti-cancer Imatinib Mesylate / 220127-57-1 Tyrosine-kinase Inhibitor

Contact Details
Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd.

Contact Person: Evelyn.Yip

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