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Anti Estrogen Steroids Tamoxifen Nolvadex 99% CAS 10540-29-1 for Body Building
Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a Selective estrogen-receptor modulator. Tamoxifen is the usual endocrine (anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.
Tamoxifen is used to treat infertility in women with anovulatory disorders. A dose of 10–40 mg per day is administered in days 3–7 of a woman's cycle.In addition, a rare condition occasionally treated with tamoxifen is retroperitoneal fibrosis.
Tamoxifen is currently used for the treatment of both early and advanced ER+ (estrogen receptor positive) breast cancer in pre- and post-menopausal women.Additionally, it is the most common hormone treatment for male breast cancer.It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease.It has been further approved for the reduction of contralateral (in the opposite breast) cancer.
Tamoxifen also increase the risk of adverse side effects. Some cases of lower-limb lymphedema have been associated with the use of tamoxifen, due to the blood clots and deep vein thrombosis (DVT) that can be caused by this medication. Resolution of the blood clots or DVT is needed before lymphedema treatment can be initiated.
|Test Items||Specification||Test Results|
|Description||White crystalline powder||White crystalline powder|
|Identification||IR , UV conform||Conform|
|Loss on drying||≤0.5ml||0.21ml|
|Residue on ignition||Not more than 0.2%||0.06ml|
|Iron||Not more than 0.005%||0.0018%|
|Heavy metals||Not more than 0.001%||0.0006%|
Total: Not more than 1.0%
Individual: Not more than 0.5%
|E-isomer||Not more than 0.3%||0.19%|
|Organic volatile impurities||Conforms||Conforms|
|Conclusion||Conform with USP30|
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Natural anti estrogen
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